Nano medicine therapeutics for targeted Gene Silencing in Ovarian cancer

Dr. Manu Smriti Singh’s interview with Bio Patrika hosting “Vigyaan Patrika”, a series of author interviews. Dr. Singh completed her Doctorate from University of Bonn. She completed her Post-Doctoral Research from Tel Aviv University and Hebrew University of Jerusalem, Israel in 2020. At present, she is a Faculty at Department of Biotechnology, Bennett University with focus on tumor microenvironment and Cancer Nano medicine. Here, Manu Smriti talks about her work titled “Therapeutic Gene Silencing Using Targeted Lipid Nanoparticles in Metastatic Ovarian Cancer” published in Small journal.

GlmU: One Step Closer towards Breaking the Great Wall of Tuberculosis

Dr. Meetu Agarwal and Dr. Vijay Soni’s joint interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Meetu and Vijay are joint-first authors on the recent research paper “Unique C-terminal extension and interactome of Mycobacterium tuberculosis GlmU impacts its in vivo function and the survival of the pathogen”, published in Biochem J (2021). In this interview, they talk about this work and its relevance in the context of the tuberculosis.

Web-building in the social spiders depends on the availability of prey

Dr. Divya Uma’s interview with Bio Patrika hosting “Vigyaan Patrika”, a series of author interviews. Dr. Divya is a behavioral ecologist at the Azim Premji University (APU), Bangalore. She teaches undergraduate courses in biology. She is interested in concepts like predator-prey interactions, mimicry, sociality in insects and spiders. When she is not teaching, she likes to paint, listen to music and get lost in the forest! Here, she talks about her recent paper titled “Influence of prey availability on web-building in the social spider Stegodyphus sarasinorum (Araneae: Eresidae)” published in the Journal of Arachnology (2021).

Role of centromeres in evolution and karyotype diversity in Candida auris

Dr. Aswathy Narayanan’s interview with Bio Patrika hosting “Vigyaan Patrika”, a series of author interviews. Dr. Narayanan pursued her doctoral research in yeast genetics, under the guidance of Dr. Md. Anaul Kabir in National Institute of Technology Calicut, Kerala. Her doctoral research was focused on the eukaryotic protein folding machinery – its functions and interactome that are conserved across species. She joined Prof. Kaustuv Sanyal’s group in Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) as a postdoctoral researcher in 2016. Incidentally, around the same time, Candida auris emerged as a fungal pathogen of concern worldwide. Under Prof. Sanyal’s mentorship, she shifted her model organism from the docile Saccharomyces cerevisiae to the multidrug-resistant superbug C. auris. She is interested in multidrug resistance, stress response pathways, and karyotype evolution in fungal pathogens and aspires to identify pathogen-specific pathways/genes which can be translated to clinical practice in the future. She currently works as Scientist-B in a multicentre project funded by Indian Council of Medical Research involving JNCASR, Post Graduate Institute of Medical Education & Research (PGIMER) and Amity University Haryana. Outside the lab, she divides her time between music, books, and her three dogs. Here, Aswathy talks about her work on Functional and comparative analysis of centromeres reveals clade-Specific genome rearrangements in Candida auris and a chromosome number change in related species published in mBio.

Bio Patrika interviews Dr. Kasoju on his thoughts about “Tissue engineering using novel cell culture inserts”

Dr. Naresh Kasoju’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Kasoju is a Scientist in Applied Biology from Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (An Institute of National Importance, Dept. of Science and Technology, Govt. of India), Thiruvananthapuram, India. Earlier, he obtained Ph.D.Continue reading “Bio Patrika interviews Dr. Kasoju on his thoughts about “Tissue engineering using novel cell culture inserts””

Bio Patrika interviews Dr. Sethi on her thoughts about “Serial in-solution digestion protocol for mass spectrometry-based glycomics and proteomics analysis”

Dr. Manveen K Sethi’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Sethi serves as Instructor of Biochemistry at the Boston University School of Medicine, USA. She did her Ph.D. at Macquarie University (MQ), Australia, under the primary supervision of Dr. Morten Thaysen-Andersen, an internationally recognized researcher in Glycobiology. During her Ph.D., she forayed into colorectal cancer (CRC) research. After her Ph.D., she was offered a postdoctoral research fellowship at Boston University School of Medicine (BUSM), USA, under Prof. Joseph Zaia, an internationally-acclaimed leader in mass spectrometry (MS) and Glycoscience, where she is currently employed in a research faculty-track position of Instructor. Her research work involves identifying and characterizing biomolecules such as proteins and glycans using mass spectrometry techniques and utilizing this information to understand biomolecular deregulation in human diseases, such as cancer and Alzheimer’s disease. Here, Manveen talks about her work titled “Serial in-solution digestion protocol for mass spectrometry-based glycomics and proteomics analysis” published as a first author in Molecular Omics (2020).

Bio Patrika interviews Dr. Mishra on her thoughts about “how dengue virus activates human microglial cells?”

Dr. Ritu Mishra’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Mishra has completed her Ph.D from CCMB, Hyderabad and moved to Max Planck Institute of Molecular Biomedicine, Germany for her post-doctoral work. She is currently working as DST-INSPIRE faculty at National Institute of Immunology, New Delhi. She has expertise in Virology, immunology and neurological research and have done extensive research on HIV, Dengue, JEV and SARS-CoV-2 viruses. She published paper titled “Dengue Virus Degrades USP33–ATF3 Axis via Extracellular Vesicles to Activate Human Microglial Cells” as a first author in The Journal of Immunology (2020).