RNA-based biosensors win a race for metabolite-sensing in cells

Dr. Sudeshna Manna’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Manna is currently a postdoctoral scholar at the group of Prof. Ming Hammond in the University of Utah, USA, where she works on RNA engineering to develop genetically encodable tools for synthetic biology, cell biology, and biotechnology applications. She pursued her Ph.D. in 2019 in the Indian Institute of Science Education and Research (IISER) Pune, India, under the supervision of Prof. S. G. Srivatsan. Her Ph.D. was focused on the chemical biology of nucleic acids, particularly on the development of nucleoside probes to understand the structure and recognition of nucleic acids in the cell-free and cellular environment. Before joining her Ph.D., she obtained her master’s and bachelor’s degrees in chemistry from the Indian Institute of Technology (IIT) Guwahati and Jadavpur University, Kolkata, India, respectively. Her research interest revolves around synthetic biology, nucleic acids, and protein-based tools for diagnostics and therapeutics and exploring new antimicrobial targets. Here, Sudeshna talks about her first author work on “Guanidine Biosensors Enable Comparison of Cellular Turn-on Kinetics of Riboswitch-Based Biosensor and Reporter” published in ACS Synthetic Biology (2021).

Wrig Nanosystems offers novel at-home-blood-testing medical devices

Wrig Nanosystems Pvt. Ltd founded by Ambar Srivastava in 2009. Based in New Delhi, Wrig Nanosystems is a bioelectronics/biosensors company developing novel at-home-blood-testing medical devices.