Tag Archives: Biosimilars

Impact of mAb Aggregation on its Biological Activity

Dr. Rozaleen Dash’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Dash completed her PhD in Biochemistry from All India Institute of Medical Sciences, New Delhi then, she joined as Scientist- B at Maulana Azad Medical College, New Delhi. Currently, she is doing Post-Doc as a ICMR-RA fellow in the Professor Anurag S Rathore Lab, Department of Chemical Engineering, Indian Institute of Technology Delhi, India. She has expertise in Functional Characterization of biotherapeutics, Comparability of Biosimilars and Drug immunogenicity. Here, she talks about her co-first author research article titled “Impact of mAb Aggregation on Its Biological Activity: Rituximab as a Case Study” published in the Journal of Pharmaceutical Sciences (2020).

Job opening in Suzhou NanoMicro Tech India Pvt ltd

Specialisation: downstream processing, MAbs, peptide Biosimilars
Desirable: willing to travel, interactions with customers, problem solving attitude, Education qualification: M.sc/M.tech Biotechnology
Experience: 5 years atleast
Location: Bangalore / Hyderabad

Bio Patrika interviews Dr. Joshi on her thoughts about “Orthogonal tools for analytical biosimilarity assessment of biotherapeutics”

Dr. Srishti Joshi’s interview with Bio Patrika hosting “Vigyan Patrika”, a series of author interviews. Dr. Joshi completed her PhD in Molecular Biology and Biochemistry from Massey University, NZ in 2015. After a brief Post Doc experience at the Systems Biology lab at Korea University, she joined DBT-COE-CBT (IIT-Delhi) in 2017 an Institute Post Doctoral Fellow in the lab of Prof. Anurag Rathore at the Centre of Excellence, Biopharmaceutical Technology (DBT-COE-CBT), Indian Institute of Technology, Delhi. She has been learning and exploring the domain of Analytics in Biotherapeutics, since. She published papers titled “An application of Nano Differential Scanning Fluorimetry for Higher Order Structure assessment between mAb originator and biosimilars: Trastuzumab and Rituximab as case studies” and “Monitoring size and oligomeric-state distribution of therapeutic mAbs by NMR and DLS: Trastuzumab as a case study” as first author in Journal of Pharmaceutical and Biomedical Analysis (2020).