Premas Biotech Pvt. Ltd has received a prestigious grant from the Bill & Melinda Gates Foundation to accelerate the development of a thermostable circRNA-based Virus-Like Particle (VLP) rabies vaccine using its proprietary D-CRYPT™ Ver 3.0 platform.
This innovation aims to address one of the toughest challenges in global health — creating vaccines that remain stable without ultra-cold storage, making them more accessible for low- and middle-income countries (LMICs) where rabies continues to pose a serious threat.
A New Era in Vaccine Design
Unlike traditional RNA vaccines that rely heavily on cold-chain systems, circRNA platforms offer enhanced stability and durability. By combining this with VLP technology, Premas is working toward a vaccine that is not only thermostable but also effective, affordable, and deployable in regions with limited healthcare infrastructure.
Prabuddha Kundu, Co-Founder & Managing Director of Premas Biotech, shared:
“This grant marks a significant milestone in advancing our circRNA-VLP vaccine platform. With D-CRYPT™ Ver 3.0, we are pushing the boundaries of what is possible in thermostable vaccine design. Our focus is to deliver innovative solutions that address pressing global health challenges and bring lasting impact to communities that need them most.”
Why It Matters
Rabies remains a 100% preventable yet fatal disease, claiming tens of thousands of lives every year, particularly in Asia and Africa. A thermostable rabies vaccine could transform prevention strategies, ensuring protection even in the most remote areas.
By leveraging its advanced platforms — D-CRYPT™, Axtex-4D™, and C-Qwence™ — Premas Biotech continues to pioneer approaches in infectious diseases, cancer, metabolic disorders, and inflammation.
This initiative is more than just vaccine development; it represents a step toward equitable global health, where life-saving solutions are not limited by geography or infrastructure.
🔗 Learn more about Premas Biotech: www.premasbiotech.com
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