SciFocus/Dec 5, 2024 — Published in PNAS, this groundbreaking study examines the evolution of global antibiotic use from 2016–2023 and projects future trends through 2030. While COVID-19 caused a temporary dip in antibiotic consumption, its rebound—particularly in middle-income nations—raises concerns for antimicrobial resistance (AMR) and global health.
“The rebound in antibiotic use post-pandemic underscores the urgent need for global strategies to curb consumption and combat antimicrobial resistance.”
Key Findings
- Global Consumption Trends: Antibiotic use grew 16.3% from 29.5 to 34.3 billion defined daily doses (DDDs) from 2016 to 2023, with a 10.6% increase in daily use rates per 1,000 inhabitants.
- Pandemic Impact:
- Consumption dropped sharply during COVID-19, especially in high-income countries.
- The rebound post-pandemic was more pronounced in middle-income nations.
- Middle-Income Nations: Rapid economic growth drove significant increases in antibiotic use, highlighting disparities in access and regulation.
- Future Projections: Without intervention, global antibiotic consumption could rise by 52.3%, reaching 75.1 billion DDDs by 2030.
Implications
- The increase in antibiotic consumption is a major driver of AMR, threatening global health.
- Investments in water, sanitation, and vaccination infrastructure are critical to reducing unnecessary antibiotic use.
This study provides vital data to guide global health policies in mitigating AMR and ensuring equitable access to essential antibiotics.
Source: https://www.pnas.org/doi/10.1073/pnas.2411919121
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